Synthesis of complex unnatural fluorine-containing amino acids
نویسندگان
چکیده
منابع مشابه
Synthesis of Indole-Derived Fluorine-Containing Amino Acids
A Brønsted acid promoted direct aminoalkylation of various indoles with trifluoromethyl oxazolidine is described. A catalytic amount of triflic acid provided straightforward access to the corresponding trifluoromethyled amino esters under mild reaction conditions and a short reaction time of 4 h. On further hydrogenolysis and hydrolysis of ester, the synthesis of indole derived unnatural triflu...
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ژورنال
عنوان ژورنال: Journal of Fluorine Chemistry
سال: 2020
ISSN: 0022-1139
DOI: 10.1016/j.jfluchem.2020.109630